Mannitol, Watson’s EZ-PressTM Mannitol DC

Watson’s EZ-PressTM Mannitol DC was formulated for direct compression tableting and has good compressibility. Applications include a direct compression diluent for tablets, capsules, and effervescent tablets. Tablets have good hardness, low friability, and rapid dissolution, tablets have good hardness and have and desirable organoleptic qualities for chewable tablets.

Mannitol is a sugar alcohol (polyol).

Benefits of Mannitol as a sweetener:
  • Taste: good flavor
  • Aftertaste: Little or none
  • Produces a cooling effect, which can create a refreshing sensation when combined with mint flavors.
  • Slow solubility and pleasant creamy mouthfeel make Mannitol an excellent choice for chewable tablets.
  • Very low Glycemic Index (GI) of 2 compared to Sucrose, which is the standard with a GI of 65.
  • Low GI may make Mannitol suitable for a diabetic diet.
  • As with all sugar alcohols, Mannitol is not metabolized in the oral cavity and therefore will not contribute toward tooth decay.
  • Mannitol is non-hygroscopic, and will not absorb moisture from the atmosphere. This makes it a good choice for use with moisture-sensitive actives.
  • Mannitol can increase the rate of tablet distegration.
  • Unlike Xylitol, Mannitol is not toxic to dogs and is often used in veterinary medicine.

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Mannitol, Watson’s EZ-PressTM Mannitol DC

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