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Kiwi fruit ingredient shown to aid digestive health

Stratum Nutrition has announced that new research demonstrating the clinical benefit of ACTAZIN, a green kiwi fruit ingredient produced by Anagenix for digestive health, has recently been published in the journal Nutrition Research. The randomised, double-blind, placebo-controlled study is said to have displayed clinically significant benefits in a healthy cohort. The study evaluated 19 healthy adult […]

Stratum Nutrition has announced that new research demonstrating the clinical benefit of ACTAZIN, a green kiwi fruit ingredient produced by Anagenix for digestive health, has recently been published in the journal Nutrition Research. The randomised, double-blind, placebo-controlled study is said to have displayed clinically significant benefits in a healthy cohort.

The study evaluated 19 healthy adult volunteers and nine volunteers with complaints of functional constipation for stool frequency and quality along with a daily diary for quality of life.  The results of this clinical trial demonstrated a statistically significant increase) in mean daily bowel movements (healthy cohort) following one month of ACTAZIN (2400 mg/day) consumption. The magnitude of effect corresponded to an approximate increase of one bowel movement per week, which is regarded as a clinically meaningful effect by the FDA.  A lower daily dose of ACTAZIN (600 mg) produced a numerically equivalent result, just missing statistical significance  across the entire group, but was statistically significant in the responder sub-group.  This suggests, said Stratum Nutrition, that a low dose (600 mg) of ACTAZIN alone could help maintain a healthy digestive system.

ACTAZIN is a powdered ingredient derived from whole New Zealand green (Actinidia deliciosa ‘Hayward’) kiwi fruit from which the skin and seeds are removed and the remaining flesh cold processed for use for the support of digestive health. Contributing to the modes of action for ACTAZIN include the presence of bioactive substances including fibre, polyphenolics, and the kiwi fruit-specific enzyme, actinidin. An additional mode of action of ACTAZIN is possibly due to its ability to serve as a substrate for endogenous gut bacteria.