ANTI OXIDANT POWER AOP
ANTI OXIDANT POWER (AOP) is a company specialized in providing cell-based assays for active ingredients and nutraceuticals testing
Innovative cell efficacy tests have been developed for evaluation of intracellular antioxidant activity (based on a patented technology allowing a controlled production of ROS within the cells). Tests are available on multiple cell models (liver, gut, skin, brain) for investigation of cellular mechanism of antioxidant action, addressing direct or indirect mechanism of action (by free radical scavenging or by ARE/Nrf2-mediated gene expression activating). Scientific reports with dose-response curves, efficacy concentrations (EC50) and comparison to standard antioxidants are provided. Screening of plant extract libraries with quantitative, reproducible and high throughput measurements of antioxidant activity can be carried on.
Customized cell-based assays are provided for evaluation of other biological functions that are relevant for nutraceutical performance, such as intestinal absorption tests performed on human intestinal cell models, and inflammatory response tests on immune cell models from peripheral blood for determination of inflammatory and anti-inflammatory cytokine production .
AOP in vitro studies can be adopted to support scientific claims, publications or marketing independently or before clinical trials.
|Primary business activity||Food Safety, Quality and Service|
|Affiliated categories:||Analysis |Antioxidant |Bioactives More|
Our Top products
Cell efficacy test for antioxidant activity evaluation:Evaluation of intracellular free radical scavenging activity by measurement of neutralization of intracellular free radicals.
Evaluation of indirect antioxidant activity or ability to activate the genetic pathway through Nrf2 transcription factor (ARE/Nrf2-mediated pathway) ,which is a natural cell defense response to oxidative stress with enhanced expression of genes coding for antioxidant proteins...