Mitoquinone Bromide CAS No.: 336184-91-9 25% purity min. for supplement ingredients

Mitoquinone bromide is an analog of Coenzyme Q10 that has been shown to have potent antioxidant activity. Mitoquinone, also known as MitoQ, is a unique form of Coenzyme Q10 (CoQ10) that specifically targets and accumulates in mitochondria, the powerhouses of the cell. Unlike conventional antioxidants that may have difficulty penetrating the mitochondrial membrane, Mitoquinone is engineered to effectively reach this important organelle where it exerts its potent antioxidant effects. Bromide is a negatively charged ion with the chemical formula Br⁻. It is an important component in a variety of chemical reactions, particularly in SN2 reactions where it can act as a nucleophile or an ionizing radical. Mitoquinone bromide is targeted to mitochondria via covalent attachment to a lipophilic triphenylphosphine cation. Due to the large mitochondrial membrane potential, the cation accumulates up to 1,000 times more in mitochondria than non-targeted antioxidants such as Coenzyme Q or its analogs, enabling the antioxidant moiety to block lipid peroxidation and protect mitochondria from oxidative damage. By selectively blocking mitochondrial oxidative damage, it prevents cell death. Mitoquinone bromide may be a useful mediator of mitochondrial oxygen consumption.