The SHIME® platform (Simulator of the Human Intestinal Microbial Ecosystem)

11 May 2026

Video

The SHIME® platform (Simulator of the Human Intestinal Microbial Ecosystem)

Discover how the SHIME® (Simulator of the Human Intestinal Microbial Ecosystem) is transforming microbiome research. The SHIME® model—a highly advanced in vitro system that simulates the human gastrointestinal tract, with a strong focus on colonic fermentation. Recognized as one of the most representative technologies available, SHIME® integrates physiological, chemical, and microbiological conditions to closely mimic the complexity of the human gut.

You’ll see how the model enables long-term studies with repeated dosing, allowing researchers to investigate how treatments interact with the gut microbiota over time and across different regions of the intestine. By providing detailed spatiotemporal insights into microbial activity and mechanisms of action, SHIME® acts as a powerful “clinical trial in vitro,” complementing and supporting in vivo research.