REVOBIOM

About us

We are a team of entrepreneurs, researchers and scientists who have developed a technology that optimises the natural evolutionary processes of micro-organisms. We want to put nature back at the heart of agricultural and industrial activities to sustain our collective future on the planet thanks to the microbial communities that constitute us.

Revobiom is based on an innovative technology resulting from ten years of fundamental research, the Microbial Evolution Machine (MEM). It enables the emergence, by natural evolution, of stable and effective interactions within microbial communities.

This technology is based on digital millifluidics, which works on the basis of “droplet trains”: a succession of droplets and gas bubbles, carried by oil. Each drop, a bioreactor, allows the cultivation of a microbial cocktail in a very homogeneous and independent way. The numerous optical sensors present in the MEM make it possible to evaluate the performance of each drop, identified and traced over time. Each train includes hundreds of these bioreactors, allowing an exhaustive exploration of the evolutionary field of possibilities.

From the performance analysis, we choose the microbial cocktails to keep. The transfer module, the heart of our technology, makes it possible to select these cocktails and to propagate them in a new train of clean drops, so that they continue their evolution, without external contamination. The most promising bioreactors will be sampled several times, unlike the less interesting ones, which will be eliminated. Cycle after cycle, the Darwinian evolution of microbiomes will then be optimized.

Our team is supported by a world-class laboratory whose expertise brings a rare degree of excellence and credibility. ESPCI is known as the “French school of the Nobels”. The diverse ecosystem of our partners, both institutional and private, helps our project gain visibility with the largest international research and innovation institutes.

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