Sponsored Content
Biocatalysts Ltd Completes First Scale Up of Speciality Enzyme for Large Pharmaceutical Company Utilising new Large-Scale Chromatography Facility
5 Aug 2024
Biocatalysts Ltd has successfully completed the large-scale manufacture of a speciality ligase for a major pharmaceutical company.
A newly installed advanced chromatography system, which the enzyme company installed at its Cardiff site last year, was used to purify the enzyme molecules after the fermentation process.
Chromatography is used to separate and concentrate a desired product from other soluble substances and to remove remaining impurities and obtain a high product purity.
The addition of large-scale chromatography to Biocatalysts’ downstream processing capabilities aligns with the multi-year manufacturing expansion plans, enabling the production of high-purity speciality enzymes in the pharmaceutical and life sciences industries as well as purifying proteins in the rapidly growing precision fermentation market.
"High purity enzymes, such as ligases and polymerases are increasingly being used in pharmaceutical and larger scale manufacturing applications. The successful scale up of this speciality ligase represents one of a number of current projects at our Cardiff site for the pharmaceutical and life sciences markets using our latest advanced purification technology" — Daren Bryce, VP of Food & Pharmaceuticals at Biocatalysts Ltd.
Companies mentioned
Related categories
Related news
The Global Food Market in 2025: Compliance & Traceability are Your Export Passport
7 Nov 2025
The global B2B Food market, valued at $31.61 Billion in 2025, demands end-to-end traceability to meet evolving regulations (like the EU's Deforestation Regulation) and consumer demand for ethical sourcing.
Read more
Process Efficiency Breakthrough: Ready-to-Use Ingredient Bases Minimize Manufacturing Waste
6 Nov 2025
Faced with persistent labor shortages and rising costs, manufacturers are adopting ready-to-use bases to streamline operations. This strategic integration boosts output, reduces waste, and guarantees product consistency across batches.
Read more
Bord Bia presents Irish dairy ingredient suppliers at Fi Europe
6 Nov 2025
Dairygold Co-operative Society, The Carbery Group, and Ornua Co-operative: Meet with sustainable producers of Irish dairy ingredients at Food ingredients Europe 2025, Hall 7.2 Stand M18.
Read more
Boosting Yeast Protein Production
5 Nov 2025
Revyve raises €24.5 million to scale up FOAK facility in Dinteloord to 1600 MT annually.
Raising total funds up to €40 million.
Yeast Proteins that mimic eggs
5 Nov 2025
Reinventing baked goods and sauces in supermarkets
Imagine a cake that's soft and moist. A cake that tastes like it was baked with loads of eggs, but doesn't contain a single gram of egg.
The Hedgehog Promise: Why Consistency is Our Core Ingredient
5 Nov 2025
Our brand story is not about us—it's about empowering your NPD team. We are your dedicated guide in the journey to scalable, clean-label product success, built on a foundation of trust and consistency.
Read more
The Allure of Morels: Premium Fungi Drive Gourmet Market Growth to $3.7 Billion
4 Nov 2025
The morel market, valued at $2.64 Billion in 2024, is projected to reach $3.71 Billion by 2031, fueled by health benefits and gourmet demand. Rehydrated morels offer the only scalable solution for this premium trend.
Read more
Beyond 'Free-From': The Clean Label Trend is Now About UPF and Sourcing Transparency
3 Nov 2025
Clean label has evolved from simple additive removal to a demand for Minimal Processing and UPF (Ultra-Processed Food) status clarity. We analyze the market to keep your brand ahead of the regulatory curve.
Read more
R&D Co-Pilot: Accelerate NPD with Integrated Scientific Formulation Support
31 Oct 2025
We move beyond merely supplying ingredients. Our R&D model offers co-development, predictive modeling, and regulatory foresight to drastically reduce your time-to-market and reformulation costs.
Read more
Mitigate Risk: The Essential Food Safety Certifications B2B Buyers Demand
30 Oct 2025
In global trade, certifications are non-negotiable. We ensure regulatory compliance and risk reduction for your supply chain through internationally recognized quality and safety standards.
Read more